In this episode, Ushma Neill interviews Nora Volkow, director of the National Institute on Drug Abuse (NIDA), about her work with trailblazing imaging studies of the brain’s frontal cortex and its dopamine-driven circuitry. Volkow has helped to reveal the neurobiological underpinnings of addiction and how drug-induced changes in brain chemistry contribute to its trademark craving, compulsion, and loss of control. Watch to hear more of Volkow’s views on the value of being an effective communicator and lessons learned from the double pandemic of opioids and COVID-19.