Molecular cloning, expression, and characterization of podocalyxin-like protein 1 from rabbit as a transmembrane protein of glomerular podocytes and vascular …
DB Kershaw, PE Thomas, BL Wharram, M Goyal… - Journal of Biological …, 1995 - ASBMB
Podocytes are responsible in part for maintaining the size and charge filtration
characteristics of the glomerular filter. The major sialoprotein of the podocyte foot process
glycocalyx is a 140-kDa sialoprotein named podocalyxin. Monoclonal antibodies raised
against isolated rabbit glomeruli that recognized a podocalyxin-like protein based upon size,
Alcian blue staining, wheat germ agglutinin binding, and distribution in renal cortex were
used to expression clone cDNAs from a rabbit glomerular library. On Northern blot the …
characteristics of the glomerular filter. The major sialoprotein of the podocyte foot process
glycocalyx is a 140-kDa sialoprotein named podocalyxin. Monoclonal antibodies raised
against isolated rabbit glomeruli that recognized a podocalyxin-like protein based upon size,
Alcian blue staining, wheat germ agglutinin binding, and distribution in renal cortex were
used to expression clone cDNAs from a rabbit glomerular library. On Northern blot the …
