Activation of mouse renin promoter by cAMP and c-Jun in a kidney-derived cell line
K Tamura, K Tanimoto, K Murakami… - Biochimica et Biophysica …, 1993 - Elsevier
We demonstrated that the mouse renin promoter from− 365 to+ 16 can mediate the
activation by cAMP and c-Jun in a kidney-cell dominant manner. Deletion analysis indicated
that the region from− 75 to− 48 was responsible for the activation by cAMP. Furthermore, the
core promoter region from− 47 to+ 16 was sufficient to confer c-Jun inducibility.
activation by cAMP and c-Jun in a kidney-cell dominant manner. Deletion analysis indicated
that the region from− 75 to− 48 was responsible for the activation by cAMP. Furthermore, the
core promoter region from− 47 to+ 16 was sufficient to confer c-Jun inducibility.