[HTML][HTML] Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells

A Shiratsuchi, Y Kawasaki, M Ikemoto, H Arai… - Journal of Biological …, 1999 - ASBMB
Rat Sertoli cells phagocytose apoptotic spermatogenic cells, which consist mostly of
spermatocytes, in primary culture by recognizing phosphatidylserine (PS) exposed on the
surface of degenerating spermatogenic cells. We compared the mode of phagocytosis using
spermatogenic cells at different stages of spermatogenesis. Spermatogenic cells were
separated into several groups based on their ploidy, with purities of 60–90%. When the
fractionated spermatogenic cell populations were subjected to a phagocytosis assay, cells …