Ectopic calcification is defined as inappropriate biomineralization occurring in soft tissues. 1
Ectopic calcifications are typically composed of calcium phosphate salts, including
hydroxyapatite, but can also consist of calcium oxalates and octacalcium phosphate as seen
in kidney stones. 2 In uremic patients, a systemic mineral imbalance is associated with
widespread ectopic calcification, referred to as metastatic calcification. 3 In the absence of a
systemic mineral imbalance, ectopic calcification is typically termed dystrophic calcification …