Background High-frequency stimulation of the subthalamic nucleus (STN) is an effective
treatment for advanced forms of Parkinson disease. Postoperative improvement of motor
parkinsonian disability is known to depend on patient selection and surgical targeting.
Objective To determine which clinical and electrophysiological variables evaluated during
the operation predict the postoperative clinical outcome of patients with Parkinson disease
treated by bilateral high-frequency stimulation of the STN. Methods Intraoperative clinical …