[HTML][HTML] MicroRNAs as immune regulators: implications for transplantation

A Harris, SM Krams, OM Martinez - American Journal of Transplantation, 2010 - Elsevier
The explosion of genetic information from recent advances in sequencing technologies,
bioinformatics and genomics highlights the importance of understanding mechanisms
involved in gene expression and regulation. Over the last decade, it has become clear that
small ribonucleic acids (RNAs) are a central component of the cellular gene regulatory
network. MicroRNAs (miRNAs) are a family of endogenous, small, noncoding single-
stranded RNA of∼ 22 nucleotides in length that act as posttranscriptional gene regulatory …