TLR9-based immunotherapy for allergic disease
T Hayashi, E Raz - The American journal of medicine, 2006 - Elsevier
A significant amount of data generated over the last few years supports the contention that
Toll-like receptor (TLR) 9-based immunotherapy is effective in the prevention and treatment
of animal models of allergic disorders. We will review here our experience with two distinct
therapeutic strategies: TLR9-based immunomodulation and TLR9-based vaccination.
Immunomodulation of allergic inflammation by TLR9 ligand (TLR9-L) is transient. It prevents
both the early and late phases of the allergic reaction in experimental models of allergic …
Toll-like receptor (TLR) 9-based immunotherapy is effective in the prevention and treatment
of animal models of allergic disorders. We will review here our experience with two distinct
therapeutic strategies: TLR9-based immunomodulation and TLR9-based vaccination.
Immunomodulation of allergic inflammation by TLR9 ligand (TLR9-L) is transient. It prevents
both the early and late phases of the allergic reaction in experimental models of allergic …