Common mechanisms of autoimmune diseases (the autoimmune tautology)

JM Anaya - Autoimmunity reviews, 2012 - Elsevier
Autoimmunity reviews, 2012Elsevier
The fact that autoimmune diseases share subphenotypes, physiopathological mechanisms
and genetic factors has been called autoimmune tautology, and indicates that they have a
common origin. The autoimmune phenotypes vary depending on the target cell and the
affected organ, gender, ancestry, trigger factors and age at onset. Ten shared characteristics
supporting this logical theory are herein reviewed.
The fact that autoimmune diseases share subphenotypes, physiopathological mechanisms and genetic factors has been called autoimmune tautology, and indicates that they have a common origin. The autoimmune phenotypes vary depending on the target cell and the affected organ, gender, ancestry, trigger factors and age at onset. Ten shared characteristics supporting this logical theory are herein reviewed.
Elsevier