Animal models of human disease: experimental autoimmune gastritis—a model for autoimmune gastritis and pernicious anemia

F Alderuccio, JW Sentry, ACJ Marshall, M Biondo… - Clinical …, 2002 - Elsevier
Human autoimmune gastritis is an organ-specific autoimmune disease of the stomach. It is
characterized by the development of disease-specific autoantibodies and a pathology that
specifically targets specialized cells within the gastric environment. The autoantigens
associated with this disease have been defined as the gastric H+/K+ ATPase and intrinsic
factor. The development of experimental disease models has been pivotal in our
contemporary understanding of autoimmunity. Here we review mouse models of …