The ontogeny of the hypothalamic-pituitary-gonadal axis is particularly characterised by
incomplete functional maturation in utero and during early postnatal life, followed by
functional regression and partial quiescence during childhood, and subsequently by final
complete maturation during puberty. This review addresses the distinctive features of testis
developmental physiology–especially in the seminiferous tubule compartment–which
explain the differences observed in testicular function and its disorders between the early …