The placental bed in pregnancies complicated by primary antiphospholipid syndrome
S Stone, R Pijnenborg, L Vercruysse, R Poston… - Placenta, 2006 - Elsevier
Pregnancy in women with primary antiphospholipid syndrome (APS) is frequently
associated with placental insufficiency leading to intrauterine growth restriction (IUGR)±fetal
death, pre-eclampsia, placental abruption, premature delivery or thrombosis. The aim of this
study was to investigate the placental bed in APS pregnancies for evidence of impaired
trophoblast invasion, endothelial cell activation (ECA) and macrophage infiltration.
METHODS: Biopsies from the presumed site of the placental bed were obtained from 12 …
associated with placental insufficiency leading to intrauterine growth restriction (IUGR)±fetal
death, pre-eclampsia, placental abruption, premature delivery or thrombosis. The aim of this
study was to investigate the placental bed in APS pregnancies for evidence of impaired
trophoblast invasion, endothelial cell activation (ECA) and macrophage infiltration.
METHODS: Biopsies from the presumed site of the placental bed were obtained from 12 …