Posttransplant lymphoproliferative disease (PTLD) is a potentially fatal complication after
(solid organ) transplantation, which is highly associated with Epstein-Barr virus (EBV). The
EBV-specific cytotoxic T cell response that is essential in controlling the virus in healthy
individuals is suppressed in transplant recipients using immunosuppressive drugs. A
primary EBV infection in EBV-seronegative patients receiving an EBV-seropositive donor
organ or a reactivation in those who are already latently infected pretransplantation can lead …