[HTML][HTML] Association of type 1 inositol 1, 4, 5-trisphosphate receptor with AKAP9 (Yotiao) and protein kinase A
H Tu, TS Tang, Z Wang, I Bezprozvanny - Journal of Biological Chemistry, 2004 - ASBMB
Inositol 1, 4, 5-trisphosphate receptors (InsP 3 R) play a key role in intracellular calcium (Ca
2+) signaling. Three InsP 3 R isoforms are expressed in mammals. Type 1 InsP 3 R (InsP 3
R1) is a predominant neuronal isoform. Neuronal InsP 3 R1 is one of the major substrates of
protein kinase A (PKA) phosphorylation. In our previous study (Tang, TS, Tu, H., Wang, Z.,
and Bezprozvanny, I.(2003) J. Neurosci. 23, 403-415) we discovered a direct association
between InsP 3 R1 and protein phosphatase 1α (PP1α). In functional experiments we …
2+) signaling. Three InsP 3 R isoforms are expressed in mammals. Type 1 InsP 3 R (InsP 3
R1) is a predominant neuronal isoform. Neuronal InsP 3 R1 is one of the major substrates of
protein kinase A (PKA) phosphorylation. In our previous study (Tang, TS, Tu, H., Wang, Z.,
and Bezprozvanny, I.(2003) J. Neurosci. 23, 403-415) we discovered a direct association
between InsP 3 R1 and protein phosphatase 1α (PP1α). In functional experiments we …
