Antimicrobial activity of neuropeptides against a range of micro-organisms from skin, oral, respiratory and gastrointestinal tract sites
IA El Karim, GJ Linden, DF Orr, FT Lundy - Journal of neuroimmunology, 2008 - Elsevier
Many neuropeptides are similar in size, amino acid composition and charge to antimicrobial
peptides. This study aimed to determine whether the neuropeptides substance P (SP),
neurokinin A (NKA), calcitonin gene-related peptide (CGRP), neuropeptide Y (NPY) and
vasoactive intestinal polypeptide (VIP), displayed antimicrobial activity against
Streptococcus mutans, Lactobacillus acidophilus, Enterococcus faecalis, Escherichia coli,
Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. SP, NPY, VIP …
peptides. This study aimed to determine whether the neuropeptides substance P (SP),
neurokinin A (NKA), calcitonin gene-related peptide (CGRP), neuropeptide Y (NPY) and
vasoactive intestinal polypeptide (VIP), displayed antimicrobial activity against
Streptococcus mutans, Lactobacillus acidophilus, Enterococcus faecalis, Escherichia coli,
Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. SP, NPY, VIP …
