[HTML][HTML] The complement C5a-C5aR1 GPCR axis in COVID-19 therapeutics
TM Woodruff, AK Shukla - Trends in immunology, 2020 - cell.com
Trends in immunology, 2020•cell.com
The current pandemic of coronavirus disease (COVID-19) caused by SARS-CoV-2 is a
significant global health challenge. A recent study by Carvelli and colleagues now
demonstrates the involvement of complement C5a and its receptor C5aR1 in disease
progression and suggests that blockade of the C5a-C5aR1 axis may represent a potential
therapeutic strategy against COVID-19.
significant global health challenge. A recent study by Carvelli and colleagues now
demonstrates the involvement of complement C5a and its receptor C5aR1 in disease
progression and suggests that blockade of the C5a-C5aR1 axis may represent a potential
therapeutic strategy against COVID-19.
The current pandemic of coronavirus disease (COVID-19) caused by SARS-CoV-2 is a significant global health challenge. A recent study by Carvelli and colleagues now demonstrates the involvement of complement C5a and its receptor C5aR1 in disease progression and suggests that blockade of the C5a-C5aR1 axis may represent a potential therapeutic strategy against COVID-19.
cell.com